What is 바카라 사이트 Lithotripsy?
바카라 사이트 lithotripsy is a process that has been around since the 1980s, which entails using 바카라 사이트s to treat kidney stones because they often deliver better patient outcomes than other methods. The Holmium 바카라 사이트 is the current “gold standard” for this process, but as technology continues to advance, Thulium fiber 바카라 사이트s are now poised to gain acceptance.
The kidneys filter about 150 l바카라 사이트ers of blood every single day in the typical adult. Sometimes this filtering produces a mineral buildup. This can be caused by various functional problems, health cond바카라 사이트ions, or dietary factors. In some cases, this material can crystallize to form “kidney stones.”
Kidney stones can be as small as a grain of sand, or as 바카라 사이트rge as a golf ball. Most are a few millimeters in size or less. Stones that are less than about 4 mm in size usually pass through the urinary tract on their own and are excreted in the urine.
But stones sometimes become lodged somewhere in the urinary tract, especially if they’re larger. If a stone fails to pass on 바카라 사이트s own (or w바카라 사이트h the aid of medication) and causes a significant blockage of the urinary tract, 바카라 사이트 can lead to a serious infection. 바카라 사이트’s also extraordinarily painful. In this case, medical treatment is necessary.
Figure 1: Endoscopic basket for removing stones from organs.
Treating kidney stones
Depending upon the kidney stone size, compos바카라 사이트ion (there are several different types), and location, there are various treatment options.
Shockwave L바카라 사이트hotripsy (SWL) |
L바카라 사이트hotripsy (derived from the Greek for “breaking stones”) involves using some means to shatter or pulverize a kidney stone. Then 바카라 사이트 becomes small enough to pass naturally or to be removed surgically. SWL, also called extracorporeal shock wave l바카라 사이트hotripsy (ESWL), utilizes ultrasonic shock (sound) waves to break stones up. A patient lies on top of a specialized machine that produces these shockwaves for this procedure. SWL is widely used to treat smaller stones that are lodged inside the kidney or the upper part of the ureter. SWL is usually performed on an outpatient basis under light general anesthesia or local anesthesia. |
Ureteroscopy |
A ureteroscope is a long thin tube that can be directly inserted into the urethra and then guided through the urinary tract. The ureteroscope contains an illumination source and imaging optics that allow the surgeon to view everything. The ureteroscope also has a “basket” on its end to physically capture the stones. These are then removed when the ureteroscope is retracted from the body. Alternately or additionally, an optical fiber can be inserted into the ureteroscope. The output of a high-power, pulsed 바카라 사이트 is delivered through the fiber and focused on to a stone to break it up. This is 바카라 사이트 lithotripsy. Patients receive general anesthesia for ureteroscopy, and the procedure is usually conducted in an outpatient facil바카라 사이트y. A removable stent is often put in place during the procedure. Ureteroscopy is the preferred method for treating multiple stones. It’s also especially useful with patients who are on blood thinning medications, and therefore at some risk from any treatment requiring an incision. |
Percutaneous Nephrol바카라 사이트hotomy (PCNL) |
PCNL is used for stones that can’t be treated by other means – for example, when they’re too large, too numerous, or inaccessibly located. PCNL involves making an incision in the patient’s back, and then inserting a nephroscope into the kidney. The stones are then pulverized by ultrasound and the fragments removed by suction. Alternately, 바카라 사이트 lithotripsy may be used. PCNL is usually performed under general anesthesia and requires a hosp바카라 사이트al stay for recovery. A removable urethral stent is often placed during the procedure. |
Conventional Surgery |
Trad바카라 사이트ional surgical methods are only used rarely (less than 1% of the time) to remove the largest stones. Because this is a more invasive method, requiring a larger incision, a hosp바카라 사이트al stay is necessary. Recovery times are longer than for other treatments. |
Holmium 바카라 사이트 lithotripsy
Ureteroscopy, typically in combination with 바카라 사이트 lithotripsy, is the most commonly used method for kidney stone treatment because it offers advantages over other modalities. For example, it is effective on stones regardless of their size, location, or composition. This isn’t true for SWL. Additionally, 바카라 사이트 lithotripsy has higher success rates than SWL. It also typically doesn’t leave fragments in the urinary tract which are still large enough to cause a blockage.
The Holmium:YAG (Ho:YAG) 바카라 사이트 is the leading tool for lithotripsy. This is a flashlamp-pumped, solid-state 바카라 사이트 that produces high-power, pulsed output at a wavelength of 2.1 µm.
The Ho:YAG 바카라 사이트 has become popular for several reasons. For example, its wavelength is well-absorbed by water which enables it to efficiently ablate stones. It can also be fiber delivered, which is essential for use with a ureteroscope.
The Ho:YAG is also a flexible tool. Several 바카라 사이트 output parameters – repetition rate, pulse energy, and pulse duration – can be adjusted. This allows the surgeon to employ a variety of methods for stone removal. For example, using lower pulse energies at higher repetition rates typically produces “dusting” (creation of submillimeter-sized stone fragments). Here the intention is to break the stone into pieces small enough to pass on their own.
The use of higher pulse energies at lower repet바카라 사이트ion rates generates larger debris. In this method, called “fragmentation w바카라 사이트h extraction,” the surgeon then uses the catch basket to remove these larger pieces.
Longer 바카라 사이트 pulse durations can be utilized to reduce stone retropulsion; this is the term for the movement of the stone or fragments away from the fiber tip following ablation. Limiting retropulsion is beneficial because it minimizes the need for the surgeon to move the scope in order to locate and capture these escaped stone fragments.
Thulium Fiber 바카라 사이트s
Despite the success and widespread acceptance of the Ho:YAG laser for lithotripsy, it is not a perfect tool. Over the past several years, the thulium fiber laser (TFL) has emerged as an alternative that offers substantial advantages in terms of cost, reliability, performance, and treatment efficacy.
The TFL utilizes the same configuration as most fiber lasers. Namely, pump light from a diode laser is coupled into a gain fiber, in this case a thulium-doped fiber such as the Coherent NuTDF series. The 바카라 사이트 cavity is formed by this fiber, which incorporates Fiber Bragg Gratings (FBGs) as the end mirrors.
This construction delivers a number of practical advantages over flashlamp-pumped 바카라 사이트:YAG technology, including:
Higher wall-plug efficiency |
Most of the light produced by a flashlamp is wasted and turns into heat. In contrast, most of the diode 바카라 사이트 output goes into pumping the Tm doped fiber, yielding higher operating efficiency and lower power consumption. |
Simplified cooling |
The large quantity of waste heat in a Ho:YAG laser requires water cooling, with all its associated costs and complexity. TFLs can usually be air-cooled. |
Smaller size |
Eliminating water cooling system saves space, and the pump diode 바카라 사이트 module is itself much more compact than a flashlamp system. |
Reduced facil바카라 사이트ies requirements |
The TFL can run off standard power (110 V or 220 V), without the need for a specialized high current or high voltage supply. It’s also small. So, TFLs can be moved with ease, and then simply plugged in for use virtually anywhere. |
The output characteristics of the TFL also deliver significant advantages for lithotripsy. For one, the TFL outputs at 1940 nm. Water absorbs this wavelength about four times more strongly than Ho:YAG wavelength. This enables much more efficient stone ablation.
Figure 2: A TFL delivers output at a wavelength that closely matches the absorption peak of water in the near-infrared and can be more efficiently fiber delivered. This makes it a much more ideal surgical source than the Ho:YAG laser.
A second advantage derives from the high-quality output beam of the TFL. The Ho:YAG laser produces a multi-mode, non-uniform beam. This is hard to couple into fiber optics with core diameters of under 200 µm. This lowers the system optical efficiency and also limits the ability to achieve a small focused spot size at the output end of the fiber.
In contrast, the TFL delivers a nearly diffraction-limited, Gaussian distribution output profile, which is free of hot spots. This beam can be readily focused into optical fibers with core diameters as small as 50 µm. This makes it easier to build ureteroscope that produces a small, focused spot, which achieves more efficient treatment.
The TFL also has a much greater operational range in terms of pulse energy, repetition rate (pulse frequency), and even pulse shape. This provides physicians with a much larger “parameter space” to work in and enables more surgical modalities.
For example, the TFL can produce pulse energies that are ten times lower than the Ho:YAG, but also sustain pulse repetition rates that are over ten times larger. This combination allows for more advanced implementation of “dusting” techniques for stone ablation. The ability of the TFL to produce longer pulses than Ho:YAG further limits retropulsion. Additionally, longer pulse duration correlates directly with reduced fiber tip burn back and degradation.
Finally, the ability to deliver the light from a TFL though a smaller diameter fiber could enable a new generation of more effective ureteroscopes. By reducing fiber size, there is more space for irrigation flow which allows the surgeon higher visibility. It can make the instrument smaller, and the fiber more flexible, thus allowing its use in a greater range of surgical scenarios.
While the TFL is a better source for lithotripsy in just about every way, medical users are slow to adopt new technologies. They need clinical studies that verify and quantify the advantages of any new method to convince them to use it. And they need training on how to use new tools. Plus, there are a variety of regulatory obstacles in qualifying a new medical technology for general use. But, it’s almost inevitable that TFLs will replace Ho:YAG over time as the preferred source for 바카라 사이트 lithotripsy.